You might call me out for nitpicking here, but CPUs don’t require system clocks A key advantage is that clockless CPUs don’t consume energy when they aren’t active. Machines based on synchronous processors, on the other hand, constantly have the “pulse” of the clock traveling through the system (and the frequency at which it “beats” determines the speed of the CPU). The pulse of the clock continuously coursing through all of the circuits also results in “wasted cycles,” meaning power is being used when the CPU isn’t doing anything, and heat is being dissipated for no reason. I think that if your intent is to simulate the brain using artificial neural networks, then the how the RAM or hard drive works is inconsequential I’ll admit that it is something worth pointing out to someone who does take the brain/computer analogy too far (which is I guess exactly who you’re targeting here) or doesn’t know much about computers or brains. Kristina MurrayKristina Murray extensive work experience that varies from programming to PR, I have come to learn that my passion is in digital transformations, digital business development and digital strategy. The analysis of data to improve an online position for any company is what drives me. – Digital Business Development / Strategy – Social networking strategy. – Digital advertising – E-Comercio